Cialis

Today, men do not need to be treated for a long time and go to the doctors if there are problems with potency. Of course, if you have serious diseases, you need to go to a specialist. But often erectile dysfunction or weak erection is the result of stress, inexperience, fatigue, lack of sleep and other non-pathological factors. In such cases, you can use a special pill, for example, Cialis.

Features of the drug

The active ingredient of Cialis is tadalafil. It enters the circulatory system, improves blood circulation in the organs of the small pelvis and penis and blocks enzymes that weaken an erection. All this stimulates potency.

Brand-name Cialis is not available to everyone because it is expensive. But this does not mean that you cannot purchase this medicine. Today, you can order generic Cialis, which is based on the same tadalafil and has the same properties. But there is a high-quality analogue which is much cheaper than the original.

Dosage and administration

The tablet should be washed down with water without chewing. The optimal dose is 20 mg. The maximum daily dose is 40 mg. The drug is valid for 36 hours. Some men even report that the effect lasting for a week. At the same time, a man will not have an uncontrolled erection, which can catch by surprise in a transport or a store. Tadalafil begins to “work” during sexual arousal.

The drug can be combined with a small amount of alcohol.

Contraindications

Before you buy Cialis, check out the contraindications to the drug:

• diseases of the gastrointestinal tract;
• kidney and liver problems;
• cardiovascular pathology;
• minor age;
• a tendency to allergies.

In most cases, tadalafil acts gently. It is well perceived by the body and is not addictive.

Consequences of an overdose

Healthy people who took a single dose of 500 mg and men with erectile dysfunction who took tadalafil 100 mg per dose had the same side effects as at lower doses. The consequences of an overdose are eliminated using standard symptomatic therapy.

Side effects

The most common complaints are headaches (11%) and dyspepsia (7%). Side effects in most cases are mild or moderate. With further use of tadalafil, they decrease.

Relatively frequent side effects are myalgia, back pain, flushing of the face, nasal congestion. Rare side effects are a pain in the eye area, eyelid edema, dizziness, conjunctival hyperemia.

Interactions

Tadalafil metabolism occurs mainly with the participation of the enzyme CYP3A4. It is able to increase the area under the curve “concentration-time” by 107%. Due to the effects of rifampicin, its decrease reaches 88%.

It is believed that the activity of tadalafil increases with exposure to protease inhibitors, erythromycin, itraconazole.

If Cialis is taken simultaneously with an antacid, then the absorption rate of the active component decreases.

The pharmacokinetics of tadalafil is not affected by an increase in the pH level of the stomach due to the administration of the H2 antagonist nizatidine.

The active substance of this drug is able to enhance the effect of nitrates. Tadalafil and nitrates affect the metabolism of cGMP and NO. The combined use of such drugs is prohibited.